Mahatma Gandhi College, Iritty, founded by Iritty Educational Society, is the realisation of a long cherished dream of the hard working and enterprising people of the region. As there was no institution for higher studies near the locality, enterprising people with a vision formed Iritty educational society in 1982 and sought the permission of the University of Calicut and Kerala government to start a new aided college. The society purchased around 17 acres of land at Keezhurkunnu, 4 k.m. away from Iritty, in between Mattannur and Iritty near the Thalassery- Mysore State Highway, as the permanent site for the proposed college. The site is noted for its scenic beauty, easy accessibility and calm atmosphere so needed for scholarly pursuits. The tranquil atmosphere that envelops the region makes it an ideal spot for the scholarly aspirants. The college started functioning on 13th July 1995. Initially College was affiliated to University of Calicut. At present the college is affiliated to Kannur University. College was accredited by NAAC with A Grade in 2016.

Prof. M. P. Lakshmanan was the founder Principal of the College. Prof. M. A. H. Khan took over the mantle from him in 2000. After his retirement in March 2003 Dr. M.J Mathew assumed office as Principal and continued in the post till 2018. It was during his period, college was accredited by NAAC with A Grade. During 2018-2019, Dr Meera M was the Principal in Charge of the College. In 2019, Dr Ajitha V assumed the office as Principal and continued in the post till 2022. From May 2022, Dr. Shijo M. Joseph served as the Principal-in-Charge from May 2022 to May 2023. Dr. Swarupa R assumed charge as Principal on June 1, 2023.